Search on: EOSINOPHIL MAJOR BASIC PROTEIN 
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Descriptor English:   Eosinophil Major Basic Protein 
Descriptor Spanish:   Proteina Mayor Básica del Eosinófilo 
Descriptor Portuguese:   Proteína Básica Maior de Eosinófilos 
Synonyms English:   Eosinophil Basic Protein
Major Basic Protein, Eosinophil  
Tree Number:   D12.776.124.486.379.500
Definition English:   One of several basic proteins released from EOSINOPHIL cytoplasmic granules. Eosinophil major basic protein is a 14-kDa cytotoxic peptide with a pI of 10.9. In addition to its direct cytotoxic effects, it stimulates the release of variety of INFLAMMATION MEDIATORS. 
Pharmacological Action:   Immunologic Factors
 
History Note English:   2005(1981) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38755 
Unique Identifier:   D047093 

Occurrence in VHL: 		 

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